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KMID : 0900920000240010109
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Korean journal of Animal Reproduction
2000 Volume.24 No. 1 p.109 ~ p.113
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Effects of Short-term Thermal Stress on the Mouse Serum Concentrations of Cortisol and Dehydroepiandrosterone Sulphate
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Cha Jung-Ho
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Abstract
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This study was carried out to investigate the effect of short-term thermal stress on the serum concentrations of cortisol and DHEAS in BALB / c male mice. Cortisol and DHEAS concentrations in serum were measured by radioimmunoassay(RIA). We found there were significantly increased in the cortisol levels in 30 min-stressed group(T30) compared with control group(p＜0.01), and then declined without significance in 120 min-stressed group (T120) compared with T30. By contrast, DHEAS levels were decreased without significance in both T30 and T120 compared with control group. Though short-term thermal stress, the continuous decline of DHEAS levels were observed. These results show that short-term thermal stress affects the serum levels of cortisol and DHEAS in mice. Furthermore, we found that DHEAS is a stress-related hormone and will be able to utilize as a stress marker.
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KEYWORD
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Short-term thermal stress, Dehydroepiandrosterone sulphate, Stress marker, Cortisol, Mouse
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